Think about this concept for a second. You can create an environment in which there is increased circulating GH, decreased protein degrading enzyme production, decreased enzymes for protein conversion to energy, and a huge increase in protein storage enzymes (where muscle is the prime storage depot). Are your eyes getting wide yet? Well, there's even more but it requires a little more explanation...
Gaining muscle through massive consumption of protein is a "live by the sword, die by the sword" kind of concept. Let me explain. The body, in an attempt to dispose of excess protein, will shift metabolic gears, so to speak, and preferentially use protein via gluconeogenesis and ketogenesis for energy. This may sound tolerable (even though we just discussed the associated toxicity) but what happens if, God forbid, you miss a meal or two? Guess what?all those enzymes sitting around chewing up all that excess protein for energy are still there, turned on full blast, using muscle for fuel at nearly the same rate that you were consuming your protein. Your gains will soon disappear via the adage "easy come, easy go."
Most of us have experienced this, especially when dieting (Hey, didn't I just see some lights come on?) but couldn't figure out what happened. Protein cycling eliminates that trap completely! What happens is that cycling protein minimizes the mechanisms for protein degradation during the low protein phase such that by the time the body begins to gear them back up again during the high protein phase (4-6 weeks later), you'll have already made enormous gains.
Then, you can start dropping your protein again, thus avoiding the cascade of catabolism FOREVER. You see, the reason I'm able to say "forever" is that each time you complete a cycle of protein manipulation you create a new "MUSCLE SETPOINT," so to speak, and become immune to the catabolic sequelae of a diet chronically high in protein.
Other benefits of protein cycling include more efficient function of the liver and kidneys and a decrease in organ size. We all know that a smaller liver is great, especially to those of us with protruding guts secondary to liver hypertrophy.5 A diet with excessive protein is one of the major culprits in hepatic hypertrophy (along with exogenous GH and oral anabolic agents, etc.). The biggest benefit is the continual and exceptional gains that can be achieved while using a lot less protein (and spending a lot less money, too). Let's recap the benefits of cycling protein:
• HUGE increases in natural GH production?up to ten times normal
• Extraordinary decreases in protein degradation
• Exceptional reductions in protein waste and use for energy
• Massive increases in protein storage as muscle
• Improved liver function?probably translating into increased IGF-1 elaboration and GH sensitivity
• Decreased liver size (with decreased gut protrusion likely)
• A new "MUSCLE SETPOINT" more resistant to catabolism
• Perpetual growth without plateaus
If you're smart, you're now drooling to hear the exact program. Well, here we go. It's simple! First, protein is gradually decreased by 50% each week. As the protein is decreased, the calories are replaced by carbohydrate, but not completely. Only one half to two-thirds of the protein calories should be replaced (metabolically, protein and carbohydrate do not provide the same amount of energy, and this concept could take an entire article so just trust me on this point).
The protein should be decreased each week until protein intake is only 40 grams per day (even though I suspect 20 grams per day may cause a more beneficial metabolic compensation). Keep the 40-gram/day protein intake for one month. During the low protein period of the cycle, increasing repetitions can cause an increase in glycogen storage enzymes in muscle. This increase in repetitions (50% more than usual) is not necessary, but why waste the opportunity to teach the muscles to overfill?
Hey, don't be afraid of losing muscle and wimp out...many of our current ideas about building muscle are stupid and based on the ideas of peons and pencil necks. For instance, I have discovered, in the literature and through self-experimentation, that muscle can be built during complete starvation...but that's another topic for another day.6 Anyway, after 4 weeks of 20-40 gm of protein per day it will be time to shock the body into growth explosion! Protein should suddenly be increased to 1 gram per pound body weight divided into four to six meals daily. See? Nothing too radical or complex there, either.
Hopefully, you'll have cash for some new clothes because I guarantee a growth spurt unlike any you've ever experienced. The high protein phase is the period that you'll realize that I have taught you how to use protein like a drug rather than just food. When I first tried this cycle out after theorizing it, my attending physician (boss/evaluator/employer) ran a prescription check just to see if I had indulged in a little anabolic script writing...no joke. I actually made drug-like gains without drugs. If you do happen to be "juiced to the hilt", you might be doing the Nationals this year after adding this regimen to your stack...I'm not kidding. Oh well, you get the point.
Continue the high protein phase for four to eight weeks, depending on when you begin to plateau (usually around week 8). Do not increase protein to overcome your plateau phase, it defeats the purpose of changing your metabolism. Cycle your protein down again and start over. The difference this time will be that you will continue to gain...trust me. I promise you eternal gains with less physiologic damage and more cash in the pocket...think about it, no one has anything to gain in any way with this program but you! Let's recap:
• Decrease protein by 50% per week until a goal of 20-40 gm of protein per day is reached.
• Replace only 1/2 to 2/3 protein calories with carb calories unless weight loss is noted.
• Remain at 20-40 gm or protein per day for four weeks.
• Increase protein to one gram per pound body weight per day immediately after four weeks of low protein intake.
• Continue this for four to eight weeks and then start over.
Here are a few pointers that I have found to be helpful through trial and error as well as solid research:
1) Consume your protein immediately after training to minimize muscle loss during the low protein phase.
2) Increase carbs during low protein phase if weight loss is noted to persist for more than four days.
3) AVOID YOHIMBINE LIKE THE PLAGUE!?IT'S A POTENT INHIBITOR OF GH SECRETION.7
4) Skip the vitamin B supplements during the low protein phase?many B vitamins increase protein use for fuel which could crush you during this phase.
5) DON'T PANIC IF YOU SMOOTH OUT A LITTLE during the low protein phase?the edema resolves after two weeks or so.
The beauty of this program is that it appears basic but is grounded in an enormous base of research. Do me a favor and photograph your results. Don't forget, if you think I'm full of it, then write or call about seeing my pics...I'd be glad to prove I'm all that I claim to be. Train hard.
T
References
1) Hyperammoniaemia. Batshaw-ML. Curr-Probl-Pediatr. 1984 Nov; 14(11): 1-69
2) Homocysteine and coronary atherosclerosis. Mayer-EL. J-Am-Card. 1996 Mar 1; 27(3): 517-27
3) Diet and nutritional factors in...CA. Sain-MS. Anticancer-Res. 1987 May-Jun; 7(3): 293-300
4) Guyton text of Physiology.
5) Differential effects...on visceral organs...in lambs. Wester-TJ. J-Anim-Sci. 1995 Jun; 73(6): 1674-88
6) Effect of food restriction on rat muscle hypertrophy... Brown-CR. Comp-Bioch- Physiol-A. 1990; 95(3): 321-4
7) Role of alpha-1 and alpha-2 adrenergic receptors in GH and prolactin response...in man. Tatar-P. Neuroendocrinology. 1984 Sep; 39(3): 275-80
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